Endocrine Abstracts

Objective: Bacalin was known as an allosteric modulator of the benzodiazepine sites of the γ-aminobutyric acid A receptor (GABAAR), which produce anxiolytic effects in mice without myorelaxant or sedative effects. Baicalin occur flavonoid found in naturally in the genus Scutellaria. It has been recently shown to exert metabolic effects by attenuating hyperglycemia-induced mitochondrial damage in β-cells in diabetic rats, high-fat diet- (HFD-) indu...

Objective: Ginsenoside or saponin, is considered as the major bioactive component mediating the therapeutic properties of Korean red ginseng (KRG). However, the exact physiological mechanism underlying anti-diabetic effects is still not fully Clarified. More than 30 different saponins together account for only about 3–4% of KRG, thereby, it is assumed that non-saponin fraction of KRG also carry potential anti-diabetic effects; however, there is no study reporting the diff...

Objective: Hemorheologic alterations or changes in blood viscosity have been suggested to play a role in the pathogenesis of diabetic microvascular complications. We measured various hemorheologic parameters in type 2 diabetes patients and assessed their possible role as a diagnostic tool for diabetic nephropathy.Methods: Four hundred-seventy patients with type 2 diabetes were included in this study. Hemorheologic parameters, including erythrocyte deform...

Objective: Hemorheologic alterations or changes in blood viscosity have been suggested to play a role in the pathogenesis of diabetic microvascular complications. We measured various hemorheologic parameters in type 2 diabetes patients and assessed their possible role as a diagnostic tool for diabetic nephropathy.Methods: Four hundred-seventy patients with type 2 diabetes were included in this study. Hemorheologic parameters, including erythrocyte deform...